KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK3
All Species:
47.58
Human Site:
Y130
Identified Species:
74.76
UniProt:
P27361
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27361
NP_001035145.1
379
43136
Y130
D
L
M
E
T
D
L
Y
K
L
L
K
S
Q
Q
Chimpanzee
Pan troglodytes
XP_510921
379
43006
Y130
D
L
M
E
T
D
L
Y
K
L
L
K
S
Q
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854045
378
42847
Y129
D
L
M
E
T
D
L
Y
K
L
L
K
S
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q63844
380
43048
Y131
D
L
M
E
T
D
L
Y
K
L
L
K
S
Q
Q
Rat
Rattus norvegicus
P21708
380
43062
Y131
D
L
M
E
T
D
L
Y
K
L
L
K
S
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989481
368
41924
Y121
D
L
M
E
T
D
L
Y
K
L
L
K
T
Q
H
Frog
Xenopus laevis
P26696
361
41238
Y116
D
L
M
E
T
D
L
Y
K
L
L
K
T
Q
H
Zebra Danio
Brachydanio rerio
NP_958915
392
44081
Y144
D
L
M
E
T
D
L
Y
K
L
L
K
T
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40417
426
49103
Y176
C
L
M
E
T
D
L
Y
K
L
L
K
T
Q
R
Honey Bee
Apis mellifera
XP_393029
371
42705
Y115
C
L
M
E
T
D
L
Y
K
L
L
K
T
Q
A
Nematode Worm
Caenorhab. elegans
P39745
444
50644
Y184
C
L
M
E
T
D
L
Y
K
L
L
K
T
Q
K
Sea Urchin
Strong. purpuratus
NP_999813
369
42176
Y119
S
L
M
E
T
D
L
Y
K
L
L
K
T
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39024
376
42833
Q133
L
M
D
T
D
L
H
Q
I
I
R
S
N
Q
P
Baker's Yeast
Sacchar. cerevisiae
P16892
353
40754
H101
E
L
M
Q
T
D
L
H
R
V
I
S
T
Q
M
Red Bread Mold
Neurospora crassa
Q96TL5
358
41225
H105
E
L
L
G
T
D
L
H
R
L
L
T
S
R
P
Conservation
Percent
Protein Identity:
100
95.7
N.A.
96.3
N.A.
96.8
97.1
N.A.
N.A.
83.1
82.3
82.4
N.A.
68.5
78.3
62.1
77.5
Protein Similarity:
100
96.8
N.A.
97.6
N.A.
97.1
97.3
N.A.
N.A.
88.3
87.5
87.2
N.A.
75.5
84.4
72.5
84.4
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
93.3
N.A.
80
80
80
80
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
100
N.A.
93.3
86.6
93.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.5
47.2
46.1
Protein Similarity:
N.A.
N.A.
N.A.
66.7
63.8
62.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
40
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
86.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% A
% Cys:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
7
0
7
94
0
0
0
0
0
0
0
0
0
% D
% Glu:
14
0
0
80
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
14
0
0
0
0
0
0
14
% H
% Ile:
0
0
0
0
0
0
0
0
7
7
7
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
80
0
0
80
0
0
7
% K
% Leu:
7
94
7
0
0
7
94
0
0
87
87
0
0
0
0
% L
% Met:
0
7
87
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% P
% Gln:
0
0
0
7
0
0
0
7
0
0
0
0
0
94
40
% Q
% Arg:
0
0
0
0
0
0
0
0
14
0
7
0
0
7
7
% R
% Ser:
7
0
0
0
0
0
0
0
0
0
0
14
40
0
0
% S
% Thr:
0
0
0
7
94
0
0
0
0
0
0
7
54
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _